Sodium hyaluronate powder, also known as hyaluronic acid or HA, is a naturally occurring substance found in the human body. It is a glycosaminoglycan, which means it is a type of large molecule composed of repeating units of sugars and amino acids. HA is one of the most abundant components of the extracellular matrix, the substance that supports cells and tissues throughout the body. It is found in many different tissues, including skin, cartilage, bone, and connective tissue.
hyaluronic acid powder is widely used in the skincare and cosmetic industry due to its unique properties. It has the ability to absorb and hold water, making it an excellent moisturizer for the skin. In addition, it helps to plump up the skin, reducing the appearance of fine lines and wrinkles. Furthermore, it has anti-inflammatory properties and can help to soothe and calm the skin.
Molecular weight: Sodium hyaluronate is available in a range of molecular weights, from very low (less than 10,000 Daltons) to very high (over 1,000,000 Daltons). The molecular weight affects its ability to penetrate the skin and its overall functionality.
Hydration: Sodium hyaluronate can hold up to 1000 times its weight in water, making it an excellent hydrating agent for the skin.
Viscosity: Sodium hyaluronate has a high viscosity, which means it is thick and gooey. This makes it ideal for use in products like gels and creams, where a thicker consistency is desirable.
Biocompatibility: Sodium hyaluronate is a naturally occurring substance in the body, which means it is well-tolerated and rarely causes allergic reactions.
Specification | Grade |
<5000 Dalton | Food Grade, Cosmetic Grade |
5,000 – 10,000 Dalton | Food Grade, Cosmetic Grade |
10,000 – 100,000 Dalton | Food Grade, Cosmetic Grade |
100,000 – 200,000 Dalton | Food Grade, Cosmetic Grade |
200,000 – 800,000 Dalton | Food Grade, Cosmetic Grade |
800,000 – 1,400,000 Dalton | Food Grade, Cosmetic Grade |
1,500,000-1,900,000 Dalton | Food Grade, Cosmetic Grade |
More Than 2,000,000 Dalton | Food Grade, Cosmetic Grade |
Items tested | Specifications | Results |
Identification | IR Identification or comparable test | Complies |
Appearance | White powder | Complies |
Transparency (in 0.1% aq.sol.,) | ≥ 99.0% | 100.0% |
pH | 6.0~7.5 | 6.2 |
Assay | ≥ 93.0% | 96.6% |
Glucuronic acid | ≥ 45.0% | 46.7% |
Molecular weight | ≥(0.5-0.8)×106Da | 0.63×106Da |
Kinematic viscosity | Actual value | 15.85mm2/s |
Intrinsic viscosity | Actual value | 12.03dL/g |
Mesh | ≥ 60 | Complies |
Purity test: | ||
Heavy metals | ≤ 20 ppm | < 20 ppm |
Arsenic | ≤ 2 ppm | < 2 ppm |
Protein | ≤ 0.1% | 0.03% |
Loss on drying | ≤ 10.0% | 8.2% |
Residue on ignition | 15.0~20.0% | 18.9% |
Microbiological purity: | ||
Total bacterial count | ≤ 100CFU/g | < 100CFU/g |
Yeasts & mold | ≤ 10CFU/g | < 10CFU/g |
E. Coli | Negative | Complies |
Staph | Negative | Complies |
Salmonella | Negative | Complies |
Pseudomonas aeruginosa | | Complies |
Conclusion: Complies with the specifications |
Skincare: Sodium hyaluronate is commonly used in skincare products, including moisturizers, serums, and masks. It helps to hydrate the skin and reduce the appearance of fine lines and wrinkles.
Cosmetics: Sodium hyaluronate is used in cosmetic products like lipsticks and mascaras to provide moisturization and volume.
Injectable fillers: Sodium hyaluronate can be injected into the skin as a dermal filler to add volume and smooth out wrinkles.
Wound healing: Sodium hyaluronate is sometimes used in wound dressings to promote healing and reduce scarring.
Eye drops: Sodium hyaluronate is used in eye drops to provide relief for dry eyes.