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Nattokinase powder, also known as Bacillus subtilis protein kinase, is a fermentation product of Bacillus subtilis and is an active protease. Currently, liquid fermentation is mainly used to produce to obtain the more active nattokinase. In vitro and in vivo experiments have shown that nattokinase can activate the conversion of urokinase into urokinase. Because of its special biological activity, nattokinase has a promising future in the nutraceutical and functional food industries.
Natto is fermented from soybean strains and has been used as a traditional health food in Japan for thousands of years. Natto originated in China during the Qin and Han dynasties and was called "edamame" in China. It was introduced to Japan by monks such as Kanzen during the Tang dynasty, and gradually spread and became popular in Japan. At present, the United States, Korea, and other European and American countries are also producing natto industrially for end-product development. Natto is rich in nutrition, which contains vitamin E, carbohydrates, protein, vitamin B, fat, calcium, vitamin B2, dietary fiber, potassium, iron, and other elements; other active substances are also produced during the fermentation process, such as natto kinase, isoflavones, lysozyme, lipase, and protease.
Type | Healthcare supplement |
Source | Natto |
Solubility | Soluble |
Cas# | 133876-92-3 |
Molecular weight | 517.122 |
Molecular formula | C20H23BCl2N2O9 |
1. Prevent and dissolve blood clots
Nattokinase has the effect of dissolving thrombosis, and it is a two-way thrombolysis. It is powerful, fast, and durable. It has a good effect on the prevention and treatment of thrombotic diseases, and can significantly reduce the condition and symptoms of ischemic cerebral apoplexy.
2. Hypotensive
Taking nattokinase in moderation is beneficial to the human body to discharge excess fat in the blood, prevent arteriosclerosis, help the middle-aged and elderly to protect the health of cardiovascular and cerebrovascular, and prevent the occurrence of coronary heart disease. Nattokinase can reduce the resistance of human blood vessels and has a certain role in regulating human blood pressure.
3. Prevention of Alzheimer's
The more common "vascular dementia" is mostly caused by the blockage of microvessels in the brain by thrombus, so taking nattokinase can dissolve the thrombus and prevent dementia.
Another common degenerative dementia, "Alzheimer's disease", is related to the abnormal accumulation of amyloid plaques in the brain and the entanglement of nerve fibers. Taking nattokinase can break down such amyloid plaques, so there are treatments and treatments available. Potential to prevent Alzheimer's disease.
4. Lower cholesterol
Nattokinase combined with red yeast rice extract can effectively reduce total cholesterol. bad cholesterol. Triglycerides and can raise good cholesterol.
Nattokinase powder, also known as Bacillus subtilis protein kinase, is a fermentation product of Bacillus subtilis and is an active protease. Currently, liquid fermentation is mainly used to produce to obtain the more active nattokinase. In vitro and in vivo experiments have shown that nattokinase can activate the conversion of urokinase into urokinase. Because of its special biological activity, nattokinase has a promising future in the nutraceutical and functional food industries.
Natto is fermented from soybean strains and has been used as a traditional health food in Japan for thousands of years. Natto originated in China during the Qin and Han dynasties and was called "edamame" in China. It was introduced to Japan by monks such as Kanzen during the Tang dynasty, and gradually spread and became popular in Japan. At present, the United States, Korea, and other European and American countries are also producing natto industrially for end-product development. Natto is rich in nutrition, which contains vitamin E, carbohydrates, protein, vitamin B, fat, calcium, vitamin B2, dietary fiber, potassium, iron, and other elements; other active substances are also produced during the fermentation process, such as natto kinase, isoflavones, lysozyme, lipase, and protease.
Type | Healthcare supplement |
Source | Natto |
Solubility | Soluble |
Cas# | 133876-92-3 |
Molecular weight | 517.122 |
Molecular formula | C20H23BCl2N2O9 |
1. Prevent and dissolve blood clots
Nattokinase has the effect of dissolving thrombosis, and it is a two-way thrombolysis. It is powerful, fast, and durable. It has a good effect on the prevention and treatment of thrombotic diseases, and can significantly reduce the condition and symptoms of ischemic cerebral apoplexy.
2. Hypotensive
Taking nattokinase in moderation is beneficial to the human body to discharge excess fat in the blood, prevent arteriosclerosis, help the middle-aged and elderly to protect the health of cardiovascular and cerebrovascular, and prevent the occurrence of coronary heart disease. Nattokinase can reduce the resistance of human blood vessels and has a certain role in regulating human blood pressure.
3. Prevention of Alzheimer's
The more common "vascular dementia" is mostly caused by the blockage of microvessels in the brain by thrombus, so taking nattokinase can dissolve the thrombus and prevent dementia.
Another common degenerative dementia, "Alzheimer's disease", is related to the abnormal accumulation of amyloid plaques in the brain and the entanglement of nerve fibers. Taking nattokinase can break down such amyloid plaques, so there are treatments and treatments available. Potential to prevent Alzheimer's disease.
4. Lower cholesterol
Nattokinase combined with red yeast rice extract can effectively reduce total cholesterol. bad cholesterol. Triglycerides and can raise good cholesterol.
Item | Specification | Result |
Physicochemical Control | ||
Assay | 20000FU/g | 20300FU/g |
Appearance | Fine powder | Complies |
Color | Light yellow to off-white | Complies |
Odor&Taste | Characteristic | Complies |
Loss on Drying | ≤5.0% | 4.43% |
Residue on Ignition | ≤5.0% | 3.21% |
Sieve Analysis | 100% pass 80 mesh | Complies |
Heavy Metals | ≤10ppm | Complies |
As | ≤2ppm | Complies |
Pb | ≤2ppm | Complies |
Hg | ≤1ppm | Complies |
Microbiological Control | ||
Total Plate | <1000CFU/g | Complies |
Yeast & Mold | <100 CFU /g | Complies |
E. Coli MPN/100g | Negative | Complies |
Salmonella | Negative | Complies |
Item | Specification | Result |
Physicochemical Control | ||
Assay | 20000FU/g | 20300FU/g |
Appearance | Fine powder | Complies |
Color | Light yellow to off-white | Complies |
Odor&Taste | Characteristic | Complies |
Loss on Drying | ≤5.0% | 4.43% |
Residue on Ignition | ≤5.0% | 3.21% |
Sieve Analysis | 100% pass 80 mesh | Complies |
Heavy Metals | ≤10ppm | Complies |
As | ≤2ppm | Complies |
Pb | ≤2ppm | Complies |
Hg | ≤1ppm | Complies |
Microbiological Control | ||
Total Plate | <1000CFU/g | Complies |
Yeast & Mold | <100 CFU /g | Complies |
E. Coli MPN/100g | Negative | Complies |
Salmonella | Negative | Complies |
The discovery of natural nattokinase originated from the famous "2:30 p.m. experiment" by Japanese scholar Dr. Sumi Yoko. In search of an ingredient that could replace traditional medicines, Xumi spent years screening and testing more than 170 foods. Finally, one day in 1980, he discovered the existence of nattokinase. That day, he suddenly thought that fibrin fermentation can produce natto, and fibrin is the more stubborn part of the blood clot. So, at 2:30 in the afternoon, Dr. Yukio Mumi added natto extract to the artificial thrombus used in the experiment. He originally planned to observe the results of the experiment the next day, but at 5:30 in the afternoon, he accidentally checked and found that 2cm was dissolved. Compared with the usual experiments with urokinase, it took nearly two days to dissolve 2cm. The experiment showed that natto extract was 19 times faster than urokinase. Therefore, Dr. Sumi Yoko called this natto extract nattokinase, and he is also known as the "father of nattokinase" by the world.
Nattokinase powder is mainly used as raw materials for health food and functional food additives.
Specification | Recommended dosage |
20000FU/g | 100mg-300mg/day |
Application | Form |
Functional food | Solid beverage,Tablet Candy |
Health food | Tablets, Capsules |
The discovery of natural nattokinase originated from the famous "2:30 p.m. experiment" by Japanese scholar Dr. Sumi Yoko. In search of an ingredient that could replace traditional medicines, Xumi spent years screening and testing more than 170 foods. Finally, one day in 1980, he discovered the existence of nattokinase. That day, he suddenly thought that fibrin fermentation can produce natto, and fibrin is the more stubborn part of the blood clot. So, at 2:30 in the afternoon, Dr. Yukio Mumi added natto extract to the artificial thrombus used in the experiment. He originally planned to observe the results of the experiment the next day, but at 5:30 in the afternoon, he accidentally checked and found that 2cm was dissolved. Compared with the usual experiments with urokinase, it took nearly two days to dissolve 2cm. The experiment showed that natto extract was 19 times faster than urokinase. Therefore, Dr. Sumi Yoko called this natto extract nattokinase, and he is also known as the "father of nattokinase" by the world.
Nattokinase powder is mainly used as raw materials for health food and functional food additives.
Specification | Recommended dosage |
20000FU/g | 100mg-300mg/day |
Application | Form |
Functional food | Solid beverage,Tablet Candy |
Health food | Tablets, Capsules |