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Polyglutamic Acid

  • Cosmetic09

  • Bolin

  • C-202209

  • 95%

  • White powder

  • Bolin

  • HPLC

  • 1kg

  • Kosher HALAL ISO2000

  • Cosmetic grade

  • 2 years

  • Bag/1kg, Drum/25kg

  • Available

  • China

  • 1000KG/ Per Month


What is Polyglutamic Acid?

Polyglutamic acid (γ-PGA for short) is a non-toxic, environment-friendly and human-friendly polymer, and is one of the most active representatives of biopolymers. It can not only be synthesized in vivo, but also has biocompatibility, biodegradability, biosafety, and can be eaten, so it is widely used in medicine, industry, life, environment and other fields.

It was first discovered that the highly viscous silk body contained in natto, a traditional food in Japan, is mainly composed of γ-PGA, so its alias is also called natto gum and natto bacteria gum. 


γ-PGA is one of the few water-soluble polyamino acids discovered so far that can be produced by microbial fermentation in nature. It is composed of D-glutamic acid and L-glutamic acid through the polymerization of γ-glutamyl bonds. It forms a polypeptide macromolecule with a general molecular weight of 10~2000kDa. Its structure is as follows:

ab5939c618a54491a86b3984b76bc6d0 (2)

Functions of Acid Polyglutamic

1. Cosmetics:

Because there are a large number of free carboxyl, amino and carbonyl functional groups on the molecular chain of γ-PGA with hydration ability, among them, the ability of carboxyl group is more obvious, and there are a large number of hydrogen bonds between the γ-PGA chains. γ-PGA has superior water retention and water retention properties. It also chelates with metal ions, has good antibacterial properties, film-forming properties, strong smoothness, and sustained release capabilities, making it ideal for use in cosmetics to enhance and prolong moisturization. In addition, γ-PGA also has the synergistic antioxidant effect of vitamin C and the whitening effect of inhibiting skin tyrosinase activity (about 50% of kojic acid).

2. Agriculture:

Polyglutamic acid has a certain ability to protect the roots of plants. Polyglutamic acid is a water-soluble polyamino acid produced by microbial fermentation in nature. Its structure is a high molecular polymer in which glutamic acid units form peptide bonds through α-amino and γ-carboxyl groups. Polyglutamic acid can also improve the resistance of crops to saline-alkali land. It can enhance the resistance to saline-alkali land by increasing the content of proline in plants and changing the ratio of potassium and sodium ions in crops.

Applications of Polyglutamic Acid powder

The molecular weight of γ-PGA and its derivatives ranges from 50,000 to 2 million Daltons, so they can be widely used in the food industry, cosmetics, health care, water treatment, wastewater treatment, hygiene products, medical and water gels, etc.

  • Water treatment - absorbent or chelating agent for heavy metals.

  • Wastewater treatment - biopolymer flocculants can replace polyacrylamide.

  • Health care - It is beneficial to the absorption of calcium in people with osteoporosis.

  • Sanitary products - as absorbents for baby diapers, feminine sanitary napkins, etc.

  • Pharmaceuticals - drug release carriers, hemostatic agents, soft tissue fillers.

Acid Polyglutamic Specifications

Poly Glutamic Acid Specification

Molecular weight range

Content (%)


Quite High Molecular Weight




High Molecular Weight



High Molecular Weight



Low Molecular Weight



Quite Low Molecular Weight



Low Molecular Weight

About 10000



Product:Polyglutamic Acid(γ-PGA)Grade:Cosmetic Grade
AppearanceWhite or off-white
StatePowder or granules,no caking
Intrinsic viscosityActual value
Loss on drying≤10.0%
Heavy metals(Pb)≤10ppm
Total bacterial count≤100CFU/g
Yeasts & mold≤20CFU/g
E. coliNegative
Pseudomonas aeruginosaNegative