What is Red Yeast Extract?

What Is Red Yeast Extract?

Red yeast rice extract is prepared from red yeast rice by solvent extraction method and ethanol as the extraction solvent. The appearance is red powder. The active ingredients mainly include lovastatin, monacolin, ergosterol, γ-aminobutyric acid, carotene, amylase, vitamins, minerals, sugars and other substances. Red yeast rice extract has high medicinal value, is non-toxic, has no side effects, and has high safety. It is a raw material for medicines and health products.

Organic red yeast rice supplement, also known as lipid-lowering red yeast rice extract, is a fermented product refined by modern biological fermentation engineering technology with high-quality non-polluting non-transgenic rice as the main raw material.

On the basis of inheriting the traditional production process of red yeast rice, the company uses modern bioengineering technology to select and breed excellent strains, and adopts advanced fermentation technology and equipment to produce functional red yeast rice series products. The produced functional red yeast rice contains rich bioactive enzymes and various physiologically active substances, such as Monacolin-K, ergosterol, γ-aminobutyric acid, plant hormones and other metabolites of Monascus fungi, which have high value, It has no toxic and side effects, and is a safe and effective raw material for health food and medicine.

Discovery And Development Of Red Yeast Rice Extract Powder

In 1979, Japanese scholars Endo et al. isolated the HMG-CoA reductase inhibitor Monacolin K from Monascus. In 1980, American researchers Alberts et al. isolated the substance Mevinolic acid with the same structure from Aspergillus terreus. The compound was transformed into Lovastatin (Mevinolin), which was marketed under the trade name "Mevacor" and was widely used, which promoted the research and development of statin drugs. After that, a variety of statin drugs were launched, among which Merck Co., Ltd. developed on the basis of lovastatin A second-generation statin was introduced: simvastatin. At present, there are nearly 10 kinds of statin drugs on the market. The clinical application of nearly two decades shows that statin drugs have the characteristics of significant curative effect and good tolerance. Side effects such as rhabdomyolysis, etc. In addition, the higher price also limits the large-scale application of this type of drug. Therefore, many people research and explore medicines with good curative effect, low price and small dosage. Natural medicine, especially traditional Chinese medicine extract is a very promising direction.

The Difference Between Pigmented Red Yeast Rice And Functional Organic Red Yeast Rice Extract

Pigment red yeast rice powder and functional red yeast rice extract are both obtained by fermenting rice through Monascus purpura. However, the characteristics of the Monascus purpura used by the two are very different, and the fermentation process is also different. The performance of the obtained products is very different, and the price of the products is very different.

The fermentation process of ordinary red yeast rice is relatively simple: after the rice is cooked, it is inoculated and fermented in a large pond. After a certain process time and temperature, it can be discharged, and then dried to become the finished red yeast rice. Prices vary. At present, this kind of red yeast rice is used as food coloring in the food industry both at home and abroad. Different from chemical coloring agents, it is a food additive without side effects. Its application is more and more extensive, and its consumption at home and abroad is also increasing.

The fermentation process of functional red yeast rice is relatively complicated: first, the bacteria must be screened, and must undergo certain conditions of cultivation, domestication and rejuvenation; Bacteria operation), and then non-open fermentation in a small container (there is a high and low temperature control process), after the process fermentation time is reached, the material can be discharged, and the functional red yeast rice can be obtained after drying. The price of its products depends on the level of Monacolin-K contained in it.

Red Yeast Rice Extract Supplement Quality Index

Analysis	Specification	Results	Test Method
Assay	Monacolin K≥3.0%	3.22%	HPLC
Appearance	Light red to dark red powder	Light red to dark red powder	Visual
Odor&Taste	Characteristic	Characteristic	Organoleptic
Sieve	100% pass 80 mesh	Complies	80 mesh screen
Loss on Drying	≤5.0%	3.68%	5g/105°C/2hrs
Ash	≤5.0%	2.46%	5g/525°C/2hrs
Heavy Metal	≤10ppm	Complies	2010
As	≤1ppm	Complies	2010(AAS)
Pb	≤1ppm	Complies	2010(AAS)
Hg	≤0.1 ppm	Complies	2010(AAS)
Cd	≤0.1 ppm	Complies	2010(AAS)
Total Plate Count	≤1000cfu/g	Complies	2010
Yeast&Mold	≤100cfu/g	Complies	2010
E.Coil	Negative	Negative	2010

The relationship between monacolin K and lovastatin

In 1979, Japanese scholar Endo and others isolated the active substance from the fermentation broth of Monascus ruber, and named it Monacolin K with the root of the Latin name of Monascus, which attracted worldwide attention. Unfortunately, their structural identification of Monacolin K did not include stereochemical work. One year later, in 1980, Albert et al. of Merck Company in the United States named the same compound isolated from the fermentation broth of Aspergillus terreus Mevinolin, included the stereochemical structure in its structural identification, and began to develop new drugs After research, Merck developed mevinolin into the first new statin drug (chemical synthesis), named it Lovastatin, and applied for a patent.

From this we can see:

Monacolin K and Lovastatin are the same compound;

Monacolin K was discovered earlier than Lovastatin;

Monacolin K is the product of Monascus fermentation;

Lovastatin is a product of Aspergillus fermentation;

Monacolin K is named after the Latin prefix Mona- of Monascus. It is a conventional name for scientific discovery and has no specificity;

Lovastatin is named by Merck Company, which is the company's proprietary name and is exclusive.

Features of Bolin Red Yeast Extract Powder

1. The raw material supplier has 40 years of red yeast rice production experience, and has witnessed the transformation of red yeast rice from pigment use to medicinal use;

2. In order to ensure food safety, instead of yellow rice for feed, we chose high-quality edible rice produced in Northeast China;

3. Through continuous innovation, a new carrier has been invented, which is the first in the industry. The product is safer, more efficient, and has more price and quality advantages;

4. The company's preferred red yeast strain has passed the authoritative identification of the Institute of Microbiology, Chinese Academy of Sciences, with excellent and stable performance;

5. All specifications are produced by fermentation, using auxiliary materials to convert high content to low content. Although the cost is advantageous, it can also meet customer testing, but it is not conducive to the efficacy of customer end products and cannot help customers gain a larger market share, because Added excipients have no effect;

6. After years of cultivation and optimization, high-quality strains have been selected, and the product has a high content of monacolin K, which is in a leading position in China;

7. Using boiling drying technology, the temperature is controlled below 60°, and the various nutrients in red yeast rice are preserved as much as possible;

8. The product quality is good, the proportion of open-loop monacolin K is high, and it is easy to be absorbed by the human body;

9. Does not contain citrinin (Citrinin), selects excellent strains and advanced production technology, and the products produced are tested by international authoritative organizations and do not contain citrinin.