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99%
White powder
Bolin
HPLC
1kg
Kosher HALAL ISO2000
Cosmetic grade
2 years
Bag/1kg, Drum/25kg
Available
China
1000KG/ Per Month
Bolin has been focusing on the research of extracts and other raw materials for more than ten years, and this product is our flagship product. Our product oils are competitively priced, of high quality, and undergo rigorous independent testing to ensure that the products supplied to the world are of the highest quality.
Tranexamic acid, also known as coagulic acid and hemostatic cyclic acid, with molecular formula C8H15NO2 and chemical name trans-4-aminomethylcyclohexanecarboxylic acid, is white crystalline powder, odorless and slightly tasty. It is easily soluble in water and almost insoluble in ethanol, acetone, trichloromethane or ether.
It is a synthetic lysine derivative that has been described by the dermatologists at Scientific Skin Care as "a powerful ingredient that brightens, lightens and lightens the complexion". Numerous studies have shown tranexamic acid to be effective in reducing pigmentation, and many well-known skincare brands have incorporated tranexamic acid into their skin lightening and spot reduction formulations.
Currently, tranexamic acid is not as well known as niacinamide and vitamin C. However, tranexamic acid has a long history of use and excellent results, and is recognized by the medical community as one of the preferred ingredients in skin whitening products.
Studies have shown that tranexamic acid is about 50 times more effective than vitamin C in melanin removal and nearly 10 times more effective than fruit acids in whitening. The whitening principle of tranexamic acid is roughly divided into two steps. Overall, tranexamic acid interferes with the production of melanin at the front end and prevents the transfer and diffusion of melanin already produced at the back end. Firstly, after the skin is stimulated by UV rays, the stratum corneum will release a prostaglandin E2 that activates melanin production; and tranexamic acid is a protease inhibitor that not only inhibits tyrosinase, but also inhibits the release of prostaglandin E2, thus preventing the accumulation of melanin. Secondly, tranexamic acid can prevent the spread of melanin to surrounding cells by inhibiting the expression of protease-activated receptors, exerting a whitening effect from the back end.
Some dermatologists describe tranexamic acid as the drug of choice for the treatment of melasma. 2012, a researcher studied the efficacy of topical tranexamic acid in the treatment of melasma and showed that there was no significant difference in the reduction of hyperpigmentation between topical 5% tranexamic acid applied twice daily compared to 2% hydroquinone over 12 weeks in the 60 patients who participated in the study. Therefore, in the treatment of melasma, tranexamic acid can be used as an adjunctive agent in combination with other drugs to achieve better pigmentation reduction.
In terms of anti-inflammation, tranexamic acid is often used in skin treatment due to its mild and stable nature. In contrast to other skin lightening ingredients, tranexamic acid can achieve anti-metamorphic and anti-inflammatory effects for people suffering from chronic eczema or dermatitis. Some studies have found that topical tranexamic acid can repair the damaged barrier function of rosacea patients and inhibit the inflammatory response by inhibiting the serine protease activity of the stratum corneum and the expression of the antimicrobial peptide LL-37, while effectively improving the pigmentation induced by rosacea, and can be used as an adjunct to rosacea treatment.
A large amount of clinical study data confirms the safety and whitening efficacy of topical tranexamic acid. However, tranexamic acid does not work as quickly in whitening and spot reduction, and it takes at least two months to see results when used alone. Therefore, combining tranexamic acid with other ingredients not only expands the efficacy of the product, but also provides a synergistic effect. Although tranexamic acid is safe for most skin types and is compatible with many other skin care ingredients, it is important to note that overuse may be irritating to some sensitive skin. Therefore, it is important to consult a dermatologist before using ingredients such as tranexamic acid. In both China and Japan, the amount of tranexamic acid used in skin care products is strictly regulated and must be between 2% and 3%.
Fibrinolysis is related to fibrinolysis and increased vascular permeability of the body in physiological or pathological states, and is also associated with the development and cure of fibrinolytic-induced reactions, various bleeding symptoms and allergic reactions. Tranexamic acid can inhibit the action of fibrinolytic enzymes and show hemostatic, anti-metabolic and anti-inflammatory effects.
1, anti-fibrinolytic effect: tranexamic acid can strongly adsorb with the lysine binding site (LBS) on the fibrin affinity site of fibrin lysozyme and fibrinogen, which inhibits the binding of fibrin lysozyme, fibrinogen and fibrin, thus strongly inhibiting the fibrin breakdown caused by fibrin lysozyme. In addition, in the presence of anti-fibrinolytic enzymes such as ɑ2-macroglobulin in serum, the antifibrinolytic effect of tranexamic acid is more obvious and the hemostatic effect is more significant.
2, hemostatic effect: abnormally hyperfibrinolytic enzymes will cause inhibition of platelet agglutination and breakdown of coagulation factors. Mild hyperactivity leads to the breakdown of fibrin first. Therefore, tranexamic acid can inhibit fibrinolysis and play a hemostatic role in general bleeding.
3、Anti-allergic reaction and anti-inflammatory effect: tranexamic acid can inhibit the production of kinins and other active peptides that cause increased vascular permeability, allergic reaction and inflammatory lesions (guinea pigs and rats).
Bolin has been focusing on the research of extracts and other raw materials for more than ten years, and this product is our flagship product. Our product oils are competitively priced, of high quality, and undergo rigorous independent testing to ensure that the products supplied to the world are of the highest quality.
Tranexamic acid, also known as coagulic acid and hemostatic cyclic acid, with molecular formula C8H15NO2 and chemical name trans-4-aminomethylcyclohexanecarboxylic acid, is white crystalline powder, odorless and slightly tasty. It is easily soluble in water and almost insoluble in ethanol, acetone, trichloromethane or ether.
It is a synthetic lysine derivative that has been described by the dermatologists at Scientific Skin Care as "a powerful ingredient that brightens, lightens and lightens the complexion". Numerous studies have shown tranexamic acid to be effective in reducing pigmentation, and many well-known skincare brands have incorporated tranexamic acid into their skin lightening and spot reduction formulations.
Currently, tranexamic acid is not as well known as niacinamide and vitamin C. However, tranexamic acid has a long history of use and excellent results, and is recognized by the medical community as one of the preferred ingredients in skin whitening products.
Studies have shown that tranexamic acid is about 50 times more effective than vitamin C in melanin removal and nearly 10 times more effective than fruit acids in whitening. The whitening principle of tranexamic acid is roughly divided into two steps. Overall, tranexamic acid interferes with the production of melanin at the front end and prevents the transfer and diffusion of melanin already produced at the back end. Firstly, after the skin is stimulated by UV rays, the stratum corneum will release a prostaglandin E2 that activates melanin production; and tranexamic acid is a protease inhibitor that not only inhibits tyrosinase, but also inhibits the release of prostaglandin E2, thus preventing the accumulation of melanin. Secondly, tranexamic acid can prevent the spread of melanin to surrounding cells by inhibiting the expression of protease-activated receptors, exerting a whitening effect from the back end.
Some dermatologists describe tranexamic acid as the drug of choice for the treatment of melasma. 2012, a researcher studied the efficacy of topical tranexamic acid in the treatment of melasma and showed that there was no significant difference in the reduction of hyperpigmentation between topical 5% tranexamic acid applied twice daily compared to 2% hydroquinone over 12 weeks in the 60 patients who participated in the study. Therefore, in the treatment of melasma, tranexamic acid can be used as an adjunctive agent in combination with other drugs to achieve better pigmentation reduction.
In terms of anti-inflammation, tranexamic acid is often used in skin treatment due to its mild and stable nature. In contrast to other skin lightening ingredients, tranexamic acid can achieve anti-metamorphic and anti-inflammatory effects for people suffering from chronic eczema or dermatitis. Some studies have found that topical tranexamic acid can repair the damaged barrier function of rosacea patients and inhibit the inflammatory response by inhibiting the serine protease activity of the stratum corneum and the expression of the antimicrobial peptide LL-37, while effectively improving the pigmentation induced by rosacea, and can be used as an adjunct to rosacea treatment.
A large amount of clinical study data confirms the safety and whitening efficacy of topical tranexamic acid. However, tranexamic acid does not work as quickly in whitening and spot reduction, and it takes at least two months to see results when used alone. Therefore, combining tranexamic acid with other ingredients not only expands the efficacy of the product, but also provides a synergistic effect. Although tranexamic acid is safe for most skin types and is compatible with many other skin care ingredients, it is important to note that overuse may be irritating to some sensitive skin. Therefore, it is important to consult a dermatologist before using ingredients such as tranexamic acid. In both China and Japan, the amount of tranexamic acid used in skin care products is strictly regulated and must be between 2% and 3%.
Fibrinolysis is related to fibrinolysis and increased vascular permeability of the body in physiological or pathological states, and is also associated with the development and cure of fibrinolytic-induced reactions, various bleeding symptoms and allergic reactions. Tranexamic acid can inhibit the action of fibrinolytic enzymes and show hemostatic, anti-metabolic and anti-inflammatory effects.
1, anti-fibrinolytic effect: tranexamic acid can strongly adsorb with the lysine binding site (LBS) on the fibrin affinity site of fibrin lysozyme and fibrinogen, which inhibits the binding of fibrin lysozyme, fibrinogen and fibrin, thus strongly inhibiting the fibrin breakdown caused by fibrin lysozyme. In addition, in the presence of anti-fibrinolytic enzymes such as ɑ2-macroglobulin in serum, the antifibrinolytic effect of tranexamic acid is more obvious and the hemostatic effect is more significant.
2, hemostatic effect: abnormally hyperfibrinolytic enzymes will cause inhibition of platelet agglutination and breakdown of coagulation factors. Mild hyperactivity leads to the breakdown of fibrin first. Therefore, tranexamic acid can inhibit fibrinolysis and play a hemostatic role in general bleeding.
3、Anti-allergic reaction and anti-inflammatory effect: tranexamic acid can inhibit the production of kinins and other active peptides that cause increased vascular permeability, allergic reaction and inflammatory lesions (guinea pigs and rats).
