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98%
White powder
Bolin
HPLC
1kg
Kosher HALAL GMP ISO2000 Organic
Food grade
2 years
Bag/1kg, Drum/25kg
Available
China
5000KG/ Per Month
Dihydromyricelin (DMY or DHM), also known as ampelopsin (AMP), ampelopsin (ampelopsin), dihydromyricetin, dihydromyricetin, Fujian tea, etc., is a kind of dihydromyricelin. Hydroflavonol flavonoids were first isolated from the leaves of Ampelopsis meliaefolia, W. T. Wang, in 1940. Dihydromyricetin is widely found in plants of the genus Serpentine of the family Snake Grape family, and the amount in vine tea can reach 30%. It also exists in Myricaceae, Rhododendron family, Garcinaceae, Euphorbiaceae, Olive family, Leguminosae, In plants such as Lymphaceae and Salicaceae. Previous studies have confirmed that dihydromyricetin has many pharmacological effects such as antioxidant, anti-tumor, anti-inflammatory, anti-alcohol and liver protection, anti-pathogenic microorganisms and blood lipid regulation. In addition, dihydromyricetin also has biological activities such as antihypertensive, inhibiting thrombosis in the body, and lowering blood sugar.
The chemical name of dihydromyricetin is (2R,3R)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-4-one, and its molecular formula is C15H12O8 , the relative molecular mass is 320.25; it is white needle-like crystal with a melting point of 245~246 ℃. It has low solubility in room temperature and cold water, easily soluble in methanol, ethanol and acetone, very slightly soluble in ethyl acetate, and insoluble in chloroform and petroleum ether.
The pharmacological effects of drugs are closely related to their chemical structural characteristics. Dihydromyricetin can undergo oxidation reactions, dehydrogenation reactions, esterification reactions, and complex reactions with metal ions. Experimental studies have confirmed that the antioxidant active center of dihydromyricetin is the phenolic hydroxyl structure located at the 3′, 4′, and 5′ positions on the B ring of its molecular structure. Although the three OH on the A ring have a certain antioxidant effect , but the antioxidant effect is relatively weak [3, 4, 5]. Metal ions can undergo a complex reaction with the acidic phenolic hydroxyl group and the carbonyl group of the complexing group in the dihydromyricetin molecule, thereby improving the antioxidant capacity of dihydromyricetin [6]. In addition, the water solubility and fat solubility of dihydromyricetin can be improved by carrying out structural modifications such as esterification, acylation, and glycosidation on the phenolic hydroxyl groups at the 3′, 4′, and 5′ positions and the hydroxyl groups at the 3, 5, and 7 positions. Or enhancing the pharmacological activity of dihydromyricetin is also one of the hot topics in dihydromyricetin research.
Dihydromyricelin (DMY or DHM), also known as ampelopsin (AMP), ampelopsin (ampelopsin), dihydromyricetin, dihydromyricetin, Fujian tea, etc., is a kind of dihydromyricelin. Hydroflavonol flavonoids were first isolated from the leaves of Ampelopsis meliaefolia, W. T. Wang, in 1940. Dihydromyricetin is widely found in plants of the genus Serpentine of the family Snake Grape family, and the amount in vine tea can reach 30%. It also exists in Myricaceae, Rhododendron family, Garcinaceae, Euphorbiaceae, Olive family, Leguminosae, In plants such as Lymphaceae and Salicaceae. Previous studies have confirmed that dihydromyricetin has many pharmacological effects such as antioxidant, anti-tumor, anti-inflammatory, anti-alcohol and liver protection, anti-pathogenic microorganisms and blood lipid regulation. In addition, dihydromyricetin also has biological activities such as antihypertensive, inhibiting thrombosis in the body, and lowering blood sugar.
The chemical name of dihydromyricetin is (2R,3R)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-4-one, and its molecular formula is C15H12O8 , the relative molecular mass is 320.25; it is white needle-like crystal with a melting point of 245~246 ℃. It has low solubility in room temperature and cold water, easily soluble in methanol, ethanol and acetone, very slightly soluble in ethyl acetate, and insoluble in chloroform and petroleum ether.
The pharmacological effects of drugs are closely related to their chemical structural characteristics. Dihydromyricetin can undergo oxidation reactions, dehydrogenation reactions, esterification reactions, and complex reactions with metal ions. Experimental studies have confirmed that the antioxidant active center of dihydromyricetin is the phenolic hydroxyl structure located at the 3′, 4′, and 5′ positions on the B ring of its molecular structure. Although the three OH on the A ring have a certain antioxidant effect , but the antioxidant effect is relatively weak [3, 4, 5]. Metal ions can undergo a complex reaction with the acidic phenolic hydroxyl group and the carbonyl group of the complexing group in the dihydromyricetin molecule, thereby improving the antioxidant capacity of dihydromyricetin [6]. In addition, the water solubility and fat solubility of dihydromyricetin can be improved by carrying out structural modifications such as esterification, acylation, and glycosidation on the phenolic hydroxyl groups at the 3′, 4′, and 5′ positions and the hydroxyl groups at the 3, 5, and 7 positions. Or enhancing the pharmacological activity of dihydromyricetin is also one of the hot topics in dihydromyricetin research.
